Report outlook: cannot open your default e-mail folders. You must connect to MX Exchange ... in Exchange Posted June 21, 2014 Hello, I've set up a VM Exchange server for an exam I have monday. I've installed outlook on a windows client. When I start outlook for the first time my name and email address appears correctly in the Add new account wizard. Then I get some certificate warning (no certificates configured yet), I click yes to proceed. Then the wizard says the email accunt is succesfully configured. So far so good. Wizard Finishes. Outlook starts. Then I get this error: Cannot open your default e-mail folders. You must connect to Microsoft Exchange with the current profile before you can synchronize your folders with your Outlook data file (.ost). I have this error on all my clients for all profiles I tried. MX Server: Vmware windows 2012 exchange 2010 dc: windows 2008r2 client vm: windows 7 x32 outlook 2010. didn't work with 2013 either. Anyone have an idea? It would be much appreciated. I've googled on this and found some stuff but nothing worked.